SCHEMBL3354286

SCHEMBL3354286

CCCCC(Br)(Br)c1c2ccccc2c(C(Br)(Br)CCCC)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
PCSK9 Q8NBP7 1/20 0.35
CES2 O00748 4/20 0.33
CES1 P23141 4/20 0.33
PGR P06401 1/20 0.33
RORA P35398 1/20 0.33
RORC P51449 1/20 0.33
RORB Q92753 1/20 0.33
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
LTA4H P09960 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2880487 0.79 GAA (0.36) TDP1L3MBTL1KDM4EALDH1A1GAA
SCHEMBL2876018 0.77 ESR1 (0.38) TDP1L3MBTL1ESR1ESR2PCSK9
SCHEMBL6686318 0.76 KIF11 (0.41) ESR1ESR2PCSK9LTA4HKIF11
SCHEMBL6680563 0.75 HTR1B (0.39) TDP1L3MBTL1KDM4EALDH1A1GAA
SCHEMBL2880457 0.74 GAA (0.38) TDP1L3MBTL1MAPTKDM4EALDH1A1
SCHEMBL2877857 0.73 GAA (0.40) TDP1L3MBTL1MAPTKDM4EALDH1A1
SCHEMBL2878596 0.73 GAA (0.40) TDP1L3MBTL1MAPTKDM4EALDH1A1
SCHEMBL2878770 0.71 GAA (0.38) CES2CES1ALDH1A1GAALTA4H
SCHEMBL6684254 0.70 KDM4E (0.38) TDP1KDM4EALDH1A1GAAHPGD
SCHEMBL6689783 0.70 SIGMAR1 (0.41) CES2CES1GAALTA4HKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732064-B2 Anthracene derivative, and light-emitting element, light-emitting device, and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-20080114178-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-05-15 US disclosed
WO-2006070897-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE SAME SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080114178-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Appliance Using the Same AFF1, NOX1, RER1 TDP1 1249/4885L3MBTL1 1878/4885ESR1 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.