Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6437032 | 0.80 | KDM4E (0.36) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL3352582 | 0.75 | CHRNB2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1686872 | 0.70 | LMNA (0.31) | — | |
| Hydrochloric Acid SCHEMBL1686826 | 0.69 | ALDH1A1 (0.34) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL4063684 | 0.65 | ALDH1A1 (0.39) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5609091 | 0.65 | KDM4E (0.41) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL7734464 | 0.65 | ALDH1A1 (0.39) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL3092658 | 0.65 | ALDH1A1 (0.39) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 | |
| SCHEMBL3965890 | 0.64 | ALDH1A1 (0.42) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL8853146 | 0.64 | ALDH1A1 (0.38) | KDM4ECYP2A6ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410231-B2 | Production process of olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100029868-A1 | PRODUCTION PROCESS OF OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-04 | — | — | US | disclosed |