Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CDK2 | P24941 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354155 | 0.89 | CDK2 (0.47) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL3355292 | 0.86 | HTR6 (0.59) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL9400557 | 0.85 | MAPT (0.51) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL13537347 | 0.84 | HTR6 (0.46) | CDK2HTR6F2RL3HTR2AHTR2C | |
| SCHEMBL29540778 | 0.83 | MAPT (0.53) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL10577625 | 0.80 | CDK2 (0.46) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL3351876 | 0.79 | CDK2 (0.48) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL3352978 | 0.77 | CACNB4 (0.56) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL11126322 | 0.77 | MAPT (0.50) | MAPTCDK2MEN1KMT2ALMNA | |
| SCHEMBL23525638 | 0.76 | CDK2 (0.53) | MAPTCDK2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |