Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354579 | 0.89 | MAPT (0.47) | CDK2MAPTCYP1A2HTR2AHTR2C | |
| SCHEMBL3352610 | 0.81 | F2RL3 (0.39) | MAPTCYP1A2HTTRXFP1LMNA | |
| SCHEMBL6947081 | 0.80 | CDK2 (0.46) | CDK2MAPTCYP1A2MEN1LMNA | |
| SCHEMBL8444605 | 0.78 | CDK2 (0.50) | CDK2MAPTCYP1A2 | |
| SCHEMBL2075237 | 0.76 | HRH3 (0.53) | CDK2MAPTMEN1LMNAKMT2A | |
| SCHEMBL3357630 | 0.76 | ALDH1A1 (0.53) | CDK2MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3356418 | 0.76 | HTR6 (0.54) | CDK2LMNASMN1; SMN2 | |
| SCHEMBL27338595 | 0.76 | HTR2A (0.45) | CDK2MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL3355292 | 0.76 | HTR6 (0.59) | CDK2MAPTHTR2AHTR2CHTR2B | |
| SCHEMBL6948323 | 0.76 | CDK2 (0.48) | CDK2MAPTCYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |