Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352559 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MEN1GAAKMT2AHPGD | |
| SCHEMBL3358563 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MEN1GAAKMT2AHPGD | |
| SCHEMBL15205388 | 0.82 | HCAR1 (0.57) | ALDH1A1MEN1GAAKMT2AHPGD | |
| SCHEMBL6246964 | 0.79 | HCAR1 (0.59) | ALDH1A1MEN1GAAKMT2AHPGD | |
| SCHEMBL21880090 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MEN1GAAKMT2AHPGD | |
| SCHEMBL17092710 | 0.79 | GPR119 (0.47) | ALDH1A1MEN1GAAKMT2AHPGD | |
| SCHEMBL1871066 | 0.78 | HCAR1 (0.54) | ALDH1A1MEN1GAAKMT2AHPGD | |
| SCHEMBL17092683 | 0.77 | GPR119 (0.61) | ALDH1A1MEN1GAAKMT2AGPR119 | |
| SCHEMBL15825020 | 0.77 | HCAR1 (0.52) | HCAR1GPR119 | |
| SCHEMBL2861894 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1MEN1GAAKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |