SCHEMBL3354969

SCHEMBL3354969

SCCCCO[SiH](Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 6/20 0.58
HDAC4 P56524 6/20 0.58
HDAC1 Q13547 6/20 0.58
HDAC7 Q8WUI4 6/20 0.58
HDAC2 Q92769 6/20 0.58
HDAC10 Q969S8 6/20 0.58
HDAC11 Q96DB2 6/20 0.58
HDAC8 Q9BY41 6/20 0.58
HDAC6 Q9UBN7 6/20 0.58
HDAC9 Q9UKV0 6/20 0.58
HDAC5 Q9UQL6 6/20 0.58
KCNA3 P22001 2/20 0.43
MMP1 P03956 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
MMP13 P45452 1/20 0.36
LTA4H P09960 2/20 0.33
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1608984 0.81 LTA4H (0.53) KCNA3LTA4HDRD2DRD3ALDH1A1
SCHEMBL5355452 0.79 LTA4H (0.53) KCNA3LTA4HDRD2DRD3ALDH1A1
SCHEMBL28429519 0.76 HDAC3 (0.95) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9498549 0.75 ALDH1A1 (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL1608013 0.75 LTA4H (0.42) KCNA3LTA4HDRD2DRD3HTR1B
SCHEMBL11222902 0.74 KCNA3 (0.73) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5679745 0.74 HDAC1 (1.00) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL5054648 0.74 HDAC1 (1.00) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL27511483 0.74 HDAC1 (1.00) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL3350917 0.73 HDAC3 (0.52) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100010166-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2010-01-14 US disclosed
EP-2064256-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2009-06-03 EP disclosed
WO-2008031895-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2008-03-20 WO disclosed