Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448170 | 0.78 | SSTR5 (0.55) | SSTR5FAAH | |
| SCHEMBL3640693 | 0.74 | FAAH (0.62) | FAAH | |
| SCHEMBL2930893 | 0.71 | CCR3 (0.58) | FAAHKDM4EMEN1KMT2A | |
| SCHEMBL171789 | 0.71 | LSS (0.58) | KDM4EMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL27610560 | 0.69 | ALDH1A1 (0.65) | LMNATSHRKMT2A | |
| SCHEMBL2451366 | 0.69 | FAAH (0.62) | FAAH | |
| SCHEMBL2447462 | 0.68 | FAAH (0.64) | FAAH | |
| SCHEMBL2448834 | 0.68 | FAAH (0.47) | FAAH | |
| SCHEMBL2932153 | 0.68 | SIGMAR1 (0.69) | FAAHKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2932104 | 0.68 | MGLL (0.57) | FAAHKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068453-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-06-17 | — | — | WO | claimed |