Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25390853 | 0.99 | ALDH1A1 (0.42) | ALDH1A1CYP4F2CYP4A11POLBTSHR | |
| SCHEMBL13459130 | 0.83 | POLB (0.44) | ALDH1A1CYP4F2CYP4A11POLBTSHR | |
| SCHEMBL17708672 | 0.81 | TSHR (0.43) | ALDH1A1POLBTSHRCYP1A2CYP2C19 | |
| SCHEMBL17708899 | 0.81 | ALDH1A1 (0.45) | ALDH1A1CYP4F2CYP4A11POLBTSHR | |
| Hydrochloric Acid SCHEMBL17709172 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP4F2CYP4A11POLBTSHR | |
| Hydrochloric Acid SCHEMBL17709174 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP4F2CYP4A11POLBTSHR | |
| SCHEMBL3530476 | 0.78 | SIRT1 (0.41) | TSHRCYP1A2ATMKMT2AMEN1 | |
| SCHEMBL3386118 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CYP4F2CYP4A11POLBTSHR | |
| SCHEMBL612174 | 0.76 | TSHR (0.63) | ALDH1A1POLBTSHRKDM4EATM | |
| SCHEMBL9129772 | 0.74 | CYP4F2 (0.52) | ALDH1A1CYP4F2CYP4A11POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168298-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | disclosed |