Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355152 | 0.83 | ALDH1A1 (0.43) | POLBKMT2AMEN1ALDH1A1CYP4F2 | |
| SCHEMBL3386118 | 0.82 | ALDH1A1 (0.40) | POLBKMT2AMEN1ALDH1A1CYP4F2 | |
| Hydrochloric Acid SCHEMBL25390853 | 0.82 | ALDH1A1 (0.42) | POLBKMT2AMEN1ALDH1A1CYP4F2 | |
| SCHEMBL3356086 | 0.79 | L3MBTL1 (0.41) | POLBKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL13459159 | 0.77 | L3MBTL1 (0.39) | POLBKMT2AMEN1ALDH1A1CYP4F2 | |
| SCHEMBL612174 | 0.75 | TSHR (0.63) | POLBKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9129772 | 0.73 | CYP4F2 (0.52) | POLBKMT2AMEN1ALDH1A1CYP4F2 | |
| SCHEMBL9739640 | 0.71 | CYP4F2 (0.67) | POLBKMT2AMEN1ALDH1A1CYP4F2 | |
| SCHEMBL7636320 | 0.71 | CYP4F2 (0.67) | POLBKMT2AMEN1ALDH1A1CYP4F2 | |
| SCHEMBL6327261 | 0.71 | KMT2A (0.41) | KMT2AMEN1ALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023512-A1 | NOVEL VANILLOID RECEPTOR MODULATORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MATRIX LABORATORIES LTD. (IN) | 2010-03-04 | — | — | WO | disclosed |