Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14876504 | 0.88 | NTSR1 (0.57) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL23631641 | 0.87 | KDM4E (0.55) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL2875571 | 0.86 | MTNR1A (0.48) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL2873285 | 0.86 | MCL1 (0.43) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL3057043 | 0.85 | MCL1 (0.41) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL13139567 | 0.83 | NTSR1 (0.45) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL21810438 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL3354646 | 0.82 | NTSR1 (0.51) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL3353214 | 0.81 | LMNA (0.44) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 | |
| SCHEMBL2869168 | 0.81 | KMT2A (0.60) | KDM4EALDH1A1HPGDPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |