Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025961 | 0.92 | DDB1 (0.56) | DDB1CRBNIKZF3GAAHSD17B10 | |
| SCHEMBL29190582 | 0.85 | DDB1 (0.58) | DDB1CRBNIKZF3GAAHSD17B10 | |
| SCHEMBL3353454 | 0.83 | DDB1 (0.51) | DDB1CRBNIKZF3GAAHSD17B10 | |
| SCHEMBL7033862 | 0.81 | GAA (0.58) | DDB1CRBNIKZF3GAAHSD17B10 | |
| SCHEMBL3356723 | 0.80 | GAA (0.69) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL1870574 | 0.79 | DDB1 (0.50) | DDB1CRBNIKZF3GAAHSD17B10 | |
| SCHEMBL1868695 | 0.79 | DDB1 (0.55) | DDB1CRBNIKZF3HCAR1ALDH1A1 | |
| SCHEMBL15531907 | 0.78 | GAA (0.55) | DDB1CRBNIKZF3GAAHSD17B10 | |
| SCHEMBL3356727 | 0.77 | GAA (0.49) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL3355563 | 0.75 | OPRM1 (0.47) | ALDH1A1OPRM1OPRL1DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |