Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352205 | 0.86 | PRMT5 (0.44) | GAAHSD17B10ALDH1A1TP53KMT2A | |
| SCHEMBL3356723 | 0.82 | GAA (0.69) | GAAHSD17B10ALDH1A1TP53HPGD | |
| SCHEMBL3356346 | 0.77 | DDB1 (0.49) | GAAHSD17B10ALDH1A1TP53HPGD | |
| SCHEMBL3357708 | 0.76 | ALDH1A1 (0.58) | GAAHSD17B10ALDH1A1TP53HPGD | |
| SCHEMBL3354425 | 0.75 | GAA (0.45) | GAAHSD17B10ALDH1A1TP53HPGD | |
| SCHEMBL30497313 | 0.71 | GAA (0.75) | GAAHSD17B10ALDH1A1TP53HPGD | |
| SCHEMBL23063522 | 0.69 | HTT (0.52) | GAAALDH1A1TP53HPGDFPR2 | |
| SCHEMBL9707233 | 0.69 | KMT2A (0.57) | GAAALDH1A1TP53HPGDNPC1 | |
| SCHEMBL30497269 | 0.68 | GAA (0.70) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL18136684 | 0.68 | GAA (0.50) | GAAHSD17B10ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |