Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063223 | 0.92 | THRB (0.54) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL231329 | 0.88 | THRB (0.59) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL230344 | 0.86 | THRB (0.56) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL8899006 | 0.86 | THRB (0.56) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL230731 | 0.86 | THRB (0.56) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL3356443 | 0.83 | THRB (0.54) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL2168203 | 0.83 | THRB (0.54) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL3358609 | 0.83 | THRB (0.54) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL1066197 | 0.83 | THRB (0.56) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL8899643 | 0.83 | HCAR2 (0.39) | THRBALDH1A1TDP1L3MBTL1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700874-A | CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE | BRIDGESTONE CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |