Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24823989 | 0.84 | AR (0.58) | KDM4EALDH1A1USP2ARTSHR | |
| SCHEMBL29549546 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1ARTSHRMAPT | |
| SCHEMBL5146047 | 0.83 | GAA (0.45) | KDM4EALDH1A1USP2ARPOLB | |
| SCHEMBL28625665 | 0.81 | AR (0.61) | ARPOLBGAAEZH2TSHR | |
| SCHEMBL5552568 | 0.81 | SMN1; SMN2 (0.47) | KDM4EALDH1A1ARTSHRMAP4K4 | |
| SCHEMBL3355529 | 0.81 | AR (0.49) | KDM4EALDH1A1USP2ARPOLB | |
| SCHEMBL20155442 | 0.80 | ALDH1A1 (0.45) | KDM4EALDH1A1USP2ARGAA | |
| SCHEMBL4329985 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1USP2POLBGAA | |
| SCHEMBL30473086 | 0.79 | ALDH1A1 (0.56) | KDM4EALDH1A1USP2POLBGAA | |
| SCHEMBL28678291 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1USP2ARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036910-A1 | HEART PROTECTION BY ADMINISTERING AN AMP-ACTIVATED PROTEIN KINASE ACTIVATOR | OHTA YOSHIKAZU (JP) | 2010-04-01 | — | — | WO | disclosed |