Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336018 | 0.84 | KDM4E (0.50) | GAAKMT2AMEN1HPGDLMNA | |
| SCHEMBL4102918 | 0.81 | GAA (0.44) | GAAKMT2AMEN1CNR2LMNA | |
| SCHEMBL4178016 | 0.78 | HTT (0.44) | GAAKMT2AMEN1CNR2HPGD | |
| SCHEMBL335269 | 0.75 | MEN1 (0.47) | GAAKMT2AMEN1HPGDLMNA | |
| SCHEMBL335542 | 0.75 | POLB (0.46) | KMT2AMEN1HPGDLMNAKDM4E | |
| SCHEMBL8902251 | 0.75 | GAA (0.44) | GAAKMT2AMEN1LMNACYP3A4 | |
| SCHEMBL4177618 | 0.75 | CTSS (0.46) | — | |
| SCHEMBL16054881 | 0.72 | GAA (0.46) | GAAKMT2AMEN1CNR2LMNA | |
| SCHEMBL15113192 | 0.70 | KMT2A (0.58) | KMT2AHPGDLMNAPOLBSMN1; SMN2 | |
| SCHEMBL27992149 | 0.69 | CNR2 (0.46) | GAAKMT2AMEN1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | disclosed |