Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4115046 | 0.80 | L3MBTL1 (0.53) | POLBKMT2AL3MBTL1PKMPTPN1 | |
| SCHEMBL336018 | 0.75 | KDM4E (0.50) | KMT2AALDH1A1KDM4ENPC1HTT | |
| SCHEMBL335774 | 0.75 | GAA (0.47) | POLBKMT2AALDH1A1KDM4EHTT | |
| SCHEMBL14210968 | 0.75 | ALDH1A1 (0.47) | POLBKMT2AL3MBTL1PKMPTPN1 | |
| SCHEMBL15291349 | 0.74 | KMT2A (0.62) | POLBKMT2AL3MBTL1PKMPTPN1 | |
| SCHEMBL2348328 | 0.73 | CTSS (0.47) | POLBKMT2AL3MBTL1PKMPTPN1 | |
| SCHEMBL335306 | 0.71 | CNR2 (0.53) | POLBKMT2AL3MBTL1PKMPTPN1 | |
| SCHEMBL15113192 | 0.69 | KMT2A (0.58) | POLBKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL2480787 | 0.67 | KMT2A (0.61) | POLBKMT2AL3MBTL1PKMPTPN1 | |
| SCHEMBL5158147 | 0.66 | KMT2A (0.60) | POLBKMT2AL3MBTL1PKMPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | disclosed |