Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829781 | 0.83 | APAF1 (0.49) | APAF1ACP3MEN1KMT2AHSD17B10 | |
| SCHEMBL8430344 | 0.83 | APAF1 (0.49) | APAF1ACP3MEN1KMT2AHSD17B10 | |
| SCHEMBL8829710 | 0.81 | NPC1 (0.52) | NPC1APAF1ACP3CYP3A4CYP2D6 | |
| SCHEMBL8430465 | 0.81 | NPC1 (0.52) | NPC1APAF1ACP3CYP3A4CYP2D6 | |
| SCHEMBL4102918 | 0.78 | GAA (0.44) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL28539345 | 0.76 | SIGMAR1 (0.46) | GAANPC1ACP3MEN1KMT2A | |
| SCHEMBL28539344 | 0.76 | SIGMAR1 (0.46) | GAANPC1ACP3MEN1KMT2A | |
| SCHEMBL4178016 | 0.75 | HTT (0.44) | GAAMEN1KMT2ACYP3A4CES2 | |
| SCHEMBL335774 | 0.75 | GAA (0.47) | GAAMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL8829775 | 0.75 | CASR (0.48) | ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686622-A | Thiazolidine derivatives, their preparation and the medicaments containing the same | RHONE-POULENC RORER S.A. (FR) | 1997-11-11 | — | — | US | disclosed |