Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29200978 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL3351612 | 0.89 | OGFRL1 (0.40) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL14923489 | 0.85 | CHEK1 (0.47) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL3358945 | 0.83 | ALOX15 (0.52) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL1871485 | 0.80 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL30271240 | 0.80 | CHEK1 (0.42) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL3353482 | 0.80 | CHEK1 (0.42) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL3352334 | 0.80 | HTR2A (0.45) | KDM4EMAPTGFERCHEK1AURKA | |
| SCHEMBL30778591 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1MAPTGFERTDP1 | |
| SCHEMBL12274589 | 0.79 | MAPK14 (0.47) | CHEK1AURKADAPK3CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |