Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.41 |
| ▸ | PDE9A | O76083 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369338 | 0.93 | PIK3CD (0.43) | KDM4EMAPTGFERALDH1A1TDP1 | |
| SCHEMBL3351612 | 0.92 | OGFRL1 (0.40) | KDM4EMAPTGFERALDH1A1TDP1 | |
| SCHEMBL25240863 | 0.86 | PIK3CD (0.55) | PIK3CD | |
| SCHEMBL1869336 | 0.86 | MEN1 (0.49) | MAPTALDH1A1TDP1PIK3CDMEN1 | |
| SCHEMBL29200978 | 0.86 | KDM4E (0.49) | KDM4EMAPTGFERALDH1A1TDP1 | |
| SCHEMBL3349663 | 0.85 | HTR1B (0.54) | PIK3CDHTR1AHTR1BHTR1FSCD | |
| SCHEMBL31482830 | 0.84 | PDE9A (0.39) | PIK3CDPDE9AHTR1AHTR1BHTR1F | |
| SCHEMBL3351511 | 0.82 | HTR1A (0.41) | KDM4EMAPTGFERPIK3CDHTR1A | |
| SCHEMBL3352822 | 0.82 | HTR1A (0.41) | PIK3CDHTR1AHTR1BHTR1FSCD | |
| SCHEMBL2980987 | 0.81 | PIK3CD (0.41) | PIK3CDPDE9AHTR1AHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062416-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062416-A1 | INHIBITORS OF KIF18A AND USES THEREOF | KIF18A, KIF18B, KIF5B | KDM4E 3550/4885MAPT 1276/4885GFER 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.