Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.38 |
| ▸ | SCD | O00767 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30778591 | 0.92 | KDM4E (0.43) | HTR1AHTR1BHTR1FKMT2AKDM4E | |
| SCHEMBL3358324 | 0.89 | KDM4E (0.41) | OGFRL1OPRM1OPRD1OPRK1KMT2A | |
| SCHEMBL3369338 | 0.85 | PIK3CD (0.43) | HTR1AHTR1BHTR1FKDM4EALDH1A1 | |
| SCHEMBL3349663 | 0.83 | HTR1B (0.54) | HTR1AHTR1BHTR1FPIK3CDSCD | |
| SCHEMBL13537393 | 0.82 | KMT2A (0.42) | OGFRL1OPRM1OPRD1OPRK1HTR1A | |
| SCHEMBL3352822 | 0.80 | HTR1A (0.41) | HTR1AHTR1BHTR1FPIK3CDSCD | |
| SCHEMBL3351511 | 0.80 | HTR1A (0.41) | HTR1AHTR1BHTR1FKDM4EMAPT | |
| SCHEMBL1863636 | 0.79 | HTR1A (0.45) | HTR1AHTR1BHTR1FPIK3CDSCD | |
| SCHEMBL25240863 | 0.79 | PIK3CD (0.55) | PIK3CD | |
| SCHEMBL1869336 | 0.79 | MEN1 (0.49) | HTR1AHTR1BHTR1FKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |