Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565215 | 0.87 | — | — | |
| Peroxymonophosphate SCHEMBL29136391 | 0.76 | BLM (0.44) | CA1CA2CA9PEPDBLM | |
| Phosphoric Acid SCHEMBL8058372 | 0.75 | CA2 (0.56) | CA1CA2CA9PEPDBLM | |
| Phosphoric Acid SCHEMBL3880757 | 0.75 | CA2 (0.56) | CA1CA2CA9PEPDBLM | |
| Phosphoric Acid SCHEMBL9678210 | 0.75 | CA2 (0.56) | CA1CA2CA9PEPDBLM | |
| Phosphoric Acid SCHEMBL23721810 | 0.75 | CA2 (0.56) | CA1CA2CA9PEPDBLM | |
| Phosphoric Acid SCHEMBL981031 | 0.75 | — | — | |
| Peroxymonophosphate SCHEMBL28594818 | 0.73 | BLM (0.41) | CA1CA2CA9PEPDBLM | |
| Bicarbonate SCHEMBL1858321 | 0.72 | CA2 (0.42) | CA1CA2CA9PEPDBLM | |
| Phosphoric Acid SCHEMBL22301393 | 0.71 | CA2 (0.50) | CA1CA2CA9PEPDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231103-A2 | PASTY INSERT MATERIAL FOR WIDENING THE GINGIVAL SULCUS AND USE THEREOF | Kettenbach GmbH & CO. KG (DE) | 2010-09-29 | — | — | EP | claimed |
| WO-2009092568-A2 | PASTY INSERT MATERIAL FOR WIDENING THE GINGIVAL SULCUS AND USE THEREOF | KETTENBACH GMBH & CO. KG (DE) | 2009-07-30 | — | — | WO | claimed |
| EP-2231103-A2 | PASTY INSERT MATERIAL FOR WIDENING THE GINGIVAL SULCUS AND USE THEREOF | Kettenbach GmbH & CO. KG (DE) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009092568-A2 | PASTY INSERT MATERIAL FOR WIDENING THE GINGIVAL SULCUS AND USE THEREOF | KETTENBACH GMBH & CO. KG (DE) | 2009-07-30 | — | — | WO | disclosed |