Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 2/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.41 |
| ▸ | F3 | P13726 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335762 | 0.94 | PYGL (0.44) | PYGLKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL335793 | 0.85 | F9 (0.50) | F9KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL336071 | 0.84 | PYGL (0.45) | PYGLKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL15282234 | 0.82 | ITK (0.38) | F9KDM4EKMT2AF7F3 | |
| SCHEMBL336483 | 0.80 | F9 (0.54) | F9F7F3 | |
| SCHEMBL334902 | 0.79 | F9 (0.49) | F9NPC1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL335308 | 0.78 | MEN1 (0.44) | NPC1RAB9AL3MBTL1KMT2AMEN1 | |
| SCHEMBL335786 | 0.77 | F9 (0.51) | F9F7F3 | |
| SCHEMBL335322 | 0.76 | F9 (0.64) | F9RAB9AF7F3 | |
| SCHEMBL335183 | 0.76 | ALDH1A1 (0.55) | F9NPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |