Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336071 | 0.94 | PYGL (0.45) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL336047 | 0.90 | POLB (0.43) | MEN1KMT2ARXFP1POLBEGFR | |
| SCHEMBL335500 | 0.89 | F9 (0.44) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL335351 | 0.88 | EGFR (0.50) | NPC1RAB9AHDAC3HDAC1LMNA | |
| SCHEMBL334843 | 0.88 | KDR (0.45) | MEN1KMT2ANPC1RAB9AKDR | |
| SCHEMBL336155 | 0.84 | TAS1R3 (0.45) | NPC1RAB9AKDRRXFP1 | |
| SCHEMBL335551 | 0.82 | KDM4E (0.43) | MEN1KMT2ANPC1RAB9AEGFR | |
| SCHEMBL335582 | 0.82 | TNIK (0.42) | KMT2ANPC1RAB9AL3MBTL1POLB | |
| SCHEMBL336586 | 0.82 | GRIN1 (0.44) | KDR | |
| SCHEMBL335390 | 0.81 | ABL1 (0.44) | MEN1KMT2ANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |