Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335308 | 0.94 | MEN1 (0.44) | NPC1RAB9AL3MBTL1KMT2AMEN1 | |
| SCHEMBL336047 | 0.90 | POLB (0.43) | PYGLACHEKMT2AMEN1 | |
| SCHEMBL335500 | 0.89 | F9 (0.44) | NPC1RAB9AL3MBTL1KMT2AMEN1 | |
| SCHEMBL335351 | 0.88 | EGFR (0.50) | PYGLKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL334843 | 0.88 | KDR (0.45) | NPC1RAB9AKMT2AMEN1HDAC1 | |
| SCHEMBL335551 | 0.87 | KDM4E (0.43) | PYGLKDM4ENPC1RAB9AMAPT | |
| SCHEMBL336155 | 0.86 | TAS1R3 (0.45) | KDM4ENPC1RAB9AMAPTBCAT1 | |
| SCHEMBL335918 | 0.84 | F9 (0.45) | PYGLPLCG2KDM4ENPC1RAB9A | |
| SCHEMBL335762 | 0.84 | PYGL (0.44) | PYGLPLCG2KDM4ENPC1RAB9A | |
| SCHEMBL335582 | 0.82 | TNIK (0.42) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |