Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR2A | P27037 | 1/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358718 | 0.75 | ACVR2A (0.59) | ACVR2ATGFBR2TSHRGCKCHRNA7 | |
| SCHEMBL3359460 | 0.74 | ACVR2A (0.61) | ACVR2ATGFBR2TSHRALDH1A1NPC1 | |
| SCHEMBL3087669 | 0.70 | ACVR2A (0.42) | ACVR2ATGFBR2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL3424283 | 0.68 | ACVR2A (0.64) | ACVR2ATGFBR2TSHRALDH1A1 | |
| SCHEMBL3091696 | 0.66 | ACVR2A (0.42) | ACVR2ATGFBR2ALDH1A1HTTNPC1 | |
| SCHEMBL3083668 | 0.65 | ACVR2A (0.41) | ACVR2ATGFBR2ALDH1A1HTT | |
| SCHEMBL412782 | 0.65 | ACVR2A (0.71) | ACVR2ATGFBR2TSHRALDH1A1NTRK1 | |
| SCHEMBL410503 | 0.64 | ACVR2A (0.68) | ACVR2ATGFBR2NPC1RAB9A | |
| SCHEMBL2815739 | 0.64 | KMT2A (0.63) | TSHRALDH1A1GAAHTTNPC1 | |
| SCHEMBL412983 | 0.63 | ACVR2A (0.40) | ACVR2ATGFBR2ALDH1A1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |