Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071572 | 0.84 | HTR2A (0.59) | HTR2A | |
| SCHEMBL1587073 | 0.83 | ALDH1A1 (0.56) | LTA4HACHE | |
| SCHEMBL1427536 | 0.83 | KDM4E (0.53) | LTA4HBCHEACHEBACE1 | |
| SCHEMBL31612484 | 0.83 | ALDH1A1 (0.54) | LTA4HBCHEACHEBACE1HTR2A | |
| SCHEMBL311417 | 0.83 | ACHE (0.61) | LTA4HBCHEACHEBACE1HTR2A | |
| SCHEMBL28444623 | 0.83 | LTA4H (0.51) | LTA4HBCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL312187 | 0.81 | ACHE (0.59) | LTA4HBCHEACHEBACE1HTR2A | |
| SCHEMBL19582434 | 0.80 | SIGMAR1 (0.58) | LTA4HACHEBACE1 | |
| SCHEMBL8117468 | 0.78 | MAPT (0.67) | — | |
| SCHEMBL5016797 | 0.78 | ACHE (0.54) | LTA4HBCHEACHEBACE1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | claimed |
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |