Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413096 | 0.76 | EGFR (0.58) | EGFRHKDC1RGS12ALDH1A1LCK | |
| Hydrochloric Acid SCHEMBL2984837 | 0.69 | EGFR (0.50) | EGFRHKDC1RGS12ALDH1A1LCK | |
| SCHEMBL7932410 | 0.68 | ESR1 (0.39) | EGFRHKDC1MAPTTDP1ALOX5 | |
| SCHEMBL11510342 | 0.67 | CA12 (0.61) | EGFRHKDC1RGS12ALDH1A1LCK | |
| SCHEMBL6258501 | 0.67 | EGFR (0.63) | EGFRRGS12ALDH1A1LCKMAPT | |
| SCHEMBL10172851 | 0.65 | EGFR (0.72) | EGFRHKDC1RGS12ALDH1A1LCK | |
| SCHEMBL4403985 | 0.65 | EGFR (0.53) | EGFRHKDC1RGS12ALDH1A1LCK | |
| SCHEMBL9163440 | 0.65 | EGFR (1.00) | EGFRHKDC1RGS12ALDH1A1LCK | |
| SCHEMBL461118 | 0.64 | EGFR (0.52) | EGFRHKDC1RGS12ALDH1A1LCK | |
| SCHEMBL11674343 | 0.64 | EGFR (0.60) | EGFRHKDC1RGS12ALDH1A1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033906-A2 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-03-25 | — | — | WO | disclosed |