SCHEMBL3360183

SCHEMBL3360183

NCCCCC(N)C(=O)NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.64
MME P08473 3/20 0.56
ITGB3 P05106 2/20 0.54
ITGA2B P08514 2/20 0.54
ERAP2 Q6P179 1/20 0.53
LNPEP Q9UIQ6 1/20 0.53
LTA4H P09960 1/20 0.52
ACE P12821 2/20 0.51
CPA1 P15085 2/20 0.51
ACE2 Q9BYF1 2/20 0.51
GNPAT O15228 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17510189 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL30688845 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL1374146 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29531496 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL1374145 1.00 MMP2 (0.64) MMP2MMEITGB3ITGA2BERAP2
Hydrochloric Acid SCHEMBL11183447 0.99 MMP2 (0.63) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29531290 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29689355 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29376846 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2
SCHEMBL29539550 0.97 MMP2 (0.62) MMP2MMEITGB3ITGA2BERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-3478121-A1 METHOD FOR SAMPLING GINGIVAL METABOLITES The Procter and Gamble Company (US) 2019-05-08 EP claimed
CN-109414109-A Method for sampling gums metabolin 宝洁公司 2019-03-01 CN claimed
US-9964472-B2 Methods for sampling gingival metabolites THE PROCTER & GAMBLE COMPANY (US) 2018-05-08 US claimed
US-20180003598-A1 METHODS FOR SAMPLING GINGIVAL METABOLITES THE PROCTER & GAMBLE COMPANY 2018-01-04 US claimed
WO-2018005335-A1 METHOD FOR SAMPLING GINGIVAL METABOLITES THE PROCTER & GAMBLE COMPANY (US) 2018-01-04 WO claimed
CN-106456633-A Sugar metabolism improving agent 三得利控股株式会社 2017-02-22 CN claimed
CN-106455664-A Composition with high content of cyclic dipeptide 三得利控股株式会社 2017-02-22 CN claimed
EP-3478121-A1 METHOD FOR SAMPLING GINGIVAL METABOLITES The Procter and Gamble Company (US) 2019-05-08 EP disclosed
US-10267797-B2 Detection of oral microbial virulence factors THE PROCTER & GAMBLE COMPANY (US) 2019-04-23 US disclosed
US-10156566-B2 Detoxification of microbial virulence factors in oral cavity THE PROCTER & GAMBLE COMPANY (US) 2018-12-18 US disclosed
US-9970934-B2 Detection of oral microbial virulence factors THE PROCTER & GAMBLE COMPANY (US) 2018-05-15 US disclosed
US-9964472-B2 Methods for sampling gingival metabolites THE PROCTER & GAMBLE COMPANY (US) 2018-05-08 US disclosed
EP-3292215-A1 DETOXIFICATION OF MICROBIAL VIRULENCE FACTORS IN ORAL CAVITY The Procter and Gamble Company (US) 2018-03-14 EP disclosed
WO-2016179561-A1 DETOXIFICATION OF MICROBIAL VIRULENCE FACTORS IN ORAL CAVITY THE PROCTER & GAMBLE COMPANY (US) 2016-11-10 WO disclosed
US-20160327557-A1 DETECTION OF ORAL MICROBIAL VIRULENCE FACTORS THE PROCTER & GAMBLE COMPANY 2016-11-10 US disclosed
EP-2794663-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2014-10-29 EP disclosed
WO-2010063124-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2010-06-10 WO disclosed
US-5346888-A To inhibit graft rejection BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-09-13 US disclosed
US-4256632-A ANTICAREINOGENIC AGENTS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1981-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10156566-B2 Detoxification of microbial virulence factors in oral cavity GSTM2, GSTA2, GSTA1 MMP2 446/4885MME 918/4885ITGB3 3083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.