Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360842 | 0.90 | HTR2C (0.59) | HTR2CHDAC8HDAC6HDAC11TDP1 | |
| SCHEMBL3361269 | 0.88 | NTSR1 (0.45) | HTR2CSCN9AHTR2A | |
| SCHEMBL4392885 | 0.83 | HTR2C (0.47) | HTR2CPRMT5MTNR1AMTNR1BKDM4E | |
| SCHEMBL4942477 | 0.81 | SCN9A (0.53) | HTR2CGRM2SCN9AHDAC8HDAC6 | |
| SCHEMBL13282968 | 0.79 | HTR2C (0.40) | HTR2CPLA2G4AHTR2A | |
| SCHEMBL3360221 | 0.79 | HTR2C (0.58) | HTR2CPRMT5HTR2A | |
| SCHEMBL4943775 | 0.77 | SCN9A (0.45) | HTR2CSCN9AERBB2HTR2A | |
| SCHEMBL3360263 | 0.76 | PDE4B (0.35) | SCN9ATDP1KDM4EMAPTKMT2A | |
| SCHEMBL29556369 | 0.75 | CDK4 (0.49) | HTR2CPRMT5KDM4EMEN1MAPT | |
| SCHEMBL3360887 | 0.75 | CDK4 (0.49) | HTR2CPRMT5KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210887-A1 | Bis resorcinyl triazine derivatives as protecting agents against UV radiation | ISDIN, S.A. (ES) | 2010-07-28 | — | — | EP | disclosed |