SCHEMBL3360263

SCHEMBL3360263

CCCCC(CC)Cn1cc(-c2nc(Cl)nc(Cl)n2)c2cc(-c3ccc(OC)cc3)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 3/20 0.35
PDE4D Q08499 3/20 0.35
PDE2A O00408 1/20 0.35
PDE9A O76083 1/20 0.35
ADORA3 P0DMS8 2/20 0.34
TLR8 Q9NR97 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
CNR2 P34972 2/20 0.33
ICMT O60725 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
GSK3B P49841 1/20 0.33
QPCT Q16769 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3361244 0.92 PDE4B (0.41) PDE4BPDE4DPDE2APDE9AKDM4E
SCHEMBL3361250 0.90 ICMT (0.37) KDM4ECNR2ICMTTP53MAPT
SCHEMBL3360889 0.84 MGLL (0.33) PDE4BPDE4DPDE2APDE9ATLR8
SCHEMBL3361360 0.80 MEN1 (0.33) PDE2APDE9ACNR2ICMTKMT2A
SCHEMBL3360975 0.80 KDM4E (0.46) PDE4BPDE4DKDM4EALDH1A1CNR2
SCHEMBL3362115 0.76 PDE4B (0.36) PDE4BPDE4DPDE2APDE9ATLR8
SCHEMBL3360192 0.76 HTR2C (0.48) PDE2APDE9ATLR8KDM4EMAPT
SCHEMBL3360208 0.73 ICMT (0.35) CNR2ICMTMAPK1HSD17B10TP53
SCHEMBL3468899 0.73 CRHR1 (0.34) PDE4BPDE4DTLR8KDM4ECNR2
SCHEMBL3359268 0.73 CRHR1 (0.34) PDE4BPDE4DTLR8KDM4ECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed