Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117516 | 0.89 | POLB (0.49) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL23843851 | 0.83 | BRD4 (0.46) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL28223501 | 0.78 | POLB (0.49) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL2981884 | 0.78 | PDE2A (0.47) | ALDH1A1USP2TSHRHSD17B10KDM4E | |
| SCHEMBL21274657 | 0.77 | POLB (0.61) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL2350824 | 0.74 | MAP2 (0.52) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL338935 | 0.74 | IDH1 (0.48) | POLBALDH1A1KDM4ELMNAGAA | |
| SCHEMBL3420123 | 0.73 | ALDH1A1 (0.48) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL10590979 | 0.73 | POLB (0.56) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL14539771 | 0.73 | KDM4E (0.44) | POLBALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076199-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDONE CARBOXYLIC ACIDS | GE HEALTHCARE AS (NO) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076199-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDONE CARBOXYLIC ACIDS | PNPO, PGD, PDXK | POLB 530/4885ALDH1A1 1170/4885USP2 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.