Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423830 | 0.87 | KDM4E (0.51) | ALDH1A1HSD17B10USP2TSHRLMNA | |
| SCHEMBL3424574 | 0.83 | SPHK2 (0.49) | ALDH1A1HSD17B10USP2TSHRHPGD | |
| SCHEMBL13339892 | 0.82 | SPHK2 (0.50) | ALDH1A1HSD17B10USP2TSHRHPGD | |
| SCHEMBL2117516 | 0.78 | POLB (0.49) | ALDH1A1HSD17B10USP2TSHRPOLB | |
| SCHEMBL5555614 | 0.77 | PDE3B (0.48) | ALDH1A1HSD17B10USP2TSHRHPGD | |
| SCHEMBL5277715 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10USP2TSHRPOLB | |
| SCHEMBL3424162 | 0.77 | MAPT (0.46) | ALDH1A1HSD17B10USP2TSHRPOLB | |
| SCHEMBL27678664 | 0.77 | PTGER1 (0.51) | HPGDLMNAPTGER1LTB4RLTB4R2 | |
| SCHEMBL10591282 | 0.75 | POLB (0.52) | ALDH1A1HSD17B10USP2TSHRPOLB | |
| SCHEMBL7216324 | 0.75 | LTA4H (0.40) | ALDH1A1HSD17B10USP2TSHRDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003959-A1 | TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER | Bayer AS (NO) | 2022-06-01 | — | — | EP | disclosed |
| EP-2816038-B1 | HOPO CHELATORS | LUMIPHORE INC (US) | 2019-11-20 | — | — | EP | disclosed |
| US-10352938-B2 | Macrocyclic HOPO chelators | LUMIPHORE, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-20160320399-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. | 2016-11-03 | — | — | US | disclosed |
| US-9273059-B2 | Macrocyclic HOPO chelators | LUMIPHORE, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| EP-2816038-A1 | Hopo chelators | Lumiphore, Inc. (US) | 2014-12-24 | — | — | EP | disclosed |
| EP-2470513-B1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE INC (US) | 2014-10-08 | — | — | EP | disclosed |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| EP-2470513-A1 | MACROCYCLIC HOPO CHELATORS | Lumiphore, Inc. (US) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011025790-A1 | MACROCYCLIC HOPO CHELATORS | LUMIPHORE, INC. (US) | 2011-03-03 | — | — | WO | disclosed |
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |
| EP-1423399-A4 | HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS | UNIV CALIFORNIA (US) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007121453-A2 | 2-HYDROXY-1-OXO 1,2 DIHYDRO ISOQUINOLINE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-25 | — | — | WO | disclosed |
| US-6846915-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-25 | — | — | US | disclosed |
| US-20050008570-A1 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-13 | — | — | US | disclosed |
| EP-1423399-A2 | HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030095922-A1 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-05-22 | — | — | US | disclosed |
| WO-2003016923-A2 | HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050008570-A1 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | HAMP, GDI1, MPI | ALDH1A1 2521/4885HSD17B10 2407/4885USP2 4038/4885 |
| US-20160320399-A1 | MACROCYCLIC HOPO CHELATORS | PHPT1, SSB, CD69 | ALDH1A1 4846/4885HSD17B10 4148/4885USP2 4239/4885 |
| US-20120214253-A1 | MACROCYCLIC HOPO CHELATORS | PHPT1, SSB, CD69 | ALDH1A1 4846/4885HSD17B10 4148/4885USP2 4239/4885 |
| US-10352938-B2 | Macrocyclic HOPO chelators | PHPT1, SSB, CD69 | ALDH1A1 4846/4885HSD17B10 4148/4885USP2 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.