Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336367 | 0.87 | MAPT (0.47) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL335948 | 0.86 | ABL1 (0.45) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL335390 | 0.86 | ABL1 (0.44) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL15282285 | 0.85 | ACP1 (0.46) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL15282212 | 0.85 | ACP1 (0.46) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL335878 | 0.85 | ABL1 (0.43) | ABL1FABP6ACP1MAPTF9 | |
| SCHEMBL335141 | 0.85 | ABL1 (0.40) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL335286 | 0.84 | ACP1 (0.42) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL335576 | 0.84 | ABL1 (0.43) | ABL1FABP6ACP1MAPTRAB9A | |
| SCHEMBL8219489 | 0.84 | F9 (0.43) | ABL1FABP6ACP1KCNK9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |