Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | FABP6 | P51161 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15282212 | 0.87 | ACP1 (0.46) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL15282285 | 0.87 | ACP1 (0.46) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL335141 | 0.85 | ABL1 (0.40) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL334912 | 0.84 | F7 (0.40) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL335570 | 0.84 | PIN1 (0.47) | ACP1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL336031 | 0.84 | ABL1 (0.41) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL335599 | 0.84 | RAB9A (0.44) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL335890 | 0.84 | ACP1 (0.40) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL335694 | 0.84 | SMN1; SMN2 (0.39) | ACP1MAPTRAB9AKMT2AMEN1 | |
| SCHEMBL335244 | 0.84 | MAPT (0.41) | ACP1MAPTRAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |