Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 5/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335599 | 0.88 | RAB9A (0.44) | ABL1FABP6TYMSACP1F7 | |
| SCHEMBL335878 | 0.87 | ABL1 (0.43) | ABL1FABP6NR2E3TYMSACP1 | |
| SCHEMBL335286 | 0.85 | ACP1 (0.42) | ABL1FABP6NR2E3TYMSACP1 | |
| SCHEMBL336031 | 0.85 | ABL1 (0.41) | ABL1FABP6NR2E3TYMSACP1 | |
| SCHEMBL335390 | 0.85 | ABL1 (0.44) | ABL1FABP6ACP1F7F9 | |
| SCHEMBL336367 | 0.84 | MAPT (0.47) | ABL1FABP6NR2E3TYMSACP1 | |
| SCHEMBL335948 | 0.84 | ABL1 (0.45) | ABL1FABP6NR2E3ACP1F7 | |
| SCHEMBL336353 | 0.83 | MAPT (0.43) | ABL1FABP6NR2E3TYMSF7 | |
| SCHEMBL8219489 | 0.83 | F9 (0.43) | ABL1FABP6TYMSACP1F7 | |
| SCHEMBL335420 | 0.83 | NPC1 (0.46) | ABL1FABP6NR2E3TYMSF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | claimed |