Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2377114 | 0.82 | HTR2A (0.53) | IDO1AKR1B1HTR2AHTR2BHTR2C | |
| SCHEMBL28620558 | 0.81 | KIF11 (0.51) | IDO1TAAR1MAOBKMT2A | |
| SCHEMBL7527885 | 0.81 | LMNA (0.55) | IDO1AKR1B1HTR2AHTR2BHTR2C | |
| SCHEMBL28213870 | 0.80 | IDO1 (0.43) | IDO1LMNATAAR1MAOBKMT2A | |
| SCHEMBL27450225 | 0.79 | GAA (0.56) | IDO1AKR1B1HTR2AHTR2BHTR2C | |
| SCHEMBL497366 | 0.77 | ACP3 (0.57) | IDO1AKR1B1HTR2AHTR2BHTR2C | |
| SCHEMBL14426935 | 0.77 | LMNA (0.52) | IDO1AKR1B1HTR2AHTR2BHTR2C | |
| SCHEMBL12898238 | 0.76 | LMNA (0.51) | IDO1AKR1B1HTR2AHTR2BHTR2C | |
| SCHEMBL20764745 | 0.76 | TXNRD1 (0.44) | IDO1LMNATAAR1KMT2A | |
| SCHEMBL10478635 | 0.76 | ACP3 (0.56) | IDO1AKR1B1HTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215050-A2 | MANUFACTURING METHOD OF 2-HYDROXY-5-PHENYLALKYLAMINOBENZOIC ACID DERIVATIVES AND THEIR SALTS | Neurotech Pharmaceuticals Co., Ltd. (KR) | 2010-08-11 | — | — | EP | claimed |
| WO-2009064084-A2 | MANUFACTURING METHOD OF 2-HYDROXY-5-PHENYLALKYLAMINOBENZOIC ACID DERIVATIVES AND THEIR SALTS | NEUROTECH CO., LTD. (KR) | 2009-05-22 | — | — | WO | claimed |
| CN-114502540-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2022-05-13 | — | — | CN | disclosed |