Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750669 | 0.88 | KIF11 (0.50) | KIF11KMT2AIDO1BCHEACHE | |
| SCHEMBL3360334 | 0.81 | IDO1 (0.47) | KMT2AIDO1MAOBTAAR1 | |
| SCHEMBL27549032 | 0.80 | YAP1 (0.41) | KMT2AIDO1BCHEACHECA1 | |
| SCHEMBL2375558 | 0.80 | KIF11 (0.59) | KIF11KMT2AIDO1BCHEACHE | |
| Hydrochloric Acid SCHEMBL28137731 | 0.79 | KIF11 (0.54) | KIF11KMT2AIDO1BCHEACHE | |
| SCHEMBL4681715 | 0.78 | CA1 (0.48) | KMT2AIDO1CA1CA2CA9 | |
| SCHEMBL14378212 | 0.78 | KIF11 (0.58) | KIF11KMT2AIDO1BCHEACHE | |
| SCHEMBL6244263 | 0.77 | KIF11 (0.49) | KIF11KMT2AIDO1BCHEACHE | |
| SCHEMBL29052387 | 0.77 | LMNA (0.42) | KMT2ACA1CA2CA9KDM4E | |
| SCHEMBL28377908 | 0.77 | L3MBTL1 (0.44) | KMT2ABCHEACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473497-B | EP4 antagonists | 卫材R&D 管理有限公司 | 2021-09-10 | — | — | CN | disclosed |