SCHEMBL3360447

SCHEMBL3360447

c1ccc2c3c(ccc2c1)NCS3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TSHR P16473 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
NOX1 Q9Y5S8 1/20 0.41
HIF1A Q16665 1/20 0.40
CYP1B1 Q16678 1/20 0.40
HPRT1 P00492 1/20 0.38
NISCH Q9Y2I1 2/20 0.33
CYP3A4 P08684 1/20 0.33
KIF11 P52732 1/20 0.32
PTPN22 Q9Y2R2 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34473434 0.74
SCHEMBL8471871 0.73 MAOA (0.41) CYP2A6TDP1ALDH1A1HSD17B10TSHR
SCHEMBL7414495 0.72 TP53 (0.43) TDP1MAPTMEN1NPC1GAA
SCHEMBL11817394 0.70 IDO1 (0.36) MAPTNISCH
SCHEMBL30874982 0.69 MAPT (0.65) CYP2A6TDP1ALDH1A1HSD17B10TSHR
SCHEMBL1790645 0.69 ALDH1A1 (0.41) CYP2A6TDP1ALDH1A1HSD17B10TSHR
Hydrochloric Acid SCHEMBL11292811 0.65 ALDH1A1 (0.41) CYP2A6TDP1ALDH1A1HSD17B10TSHR
SCHEMBL3360445 0.65 ALDH1A1 (0.41) CYP2A6TDP1ALDH1A1HSD17B10TSHR
SCHEMBL31243465 0.65 ALDH1A1 (0.41) CYP2A6TDP1ALDH1A1HSD17B10TSHR
SCHEMBL3071035 0.64 HSD17B10 (0.44) CYP2A6TDP1ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3856195-A1 METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED IMPAIRMENTS USING CCR3-INHIBITORS Alkahest, Inc. (US) 2021-08-04 EP claimed
WO-2020069008-A1 METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED IMPAIRMENTS USING CCR3-INHIBITORS ALKAHEST, INC. (US) 2020-04-02 WO claimed
EP-3606525-A1 METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED IMPAIRMENTS USING CCR3-INHIBITORS Alkahest, Inc. (US) 2020-02-12 EP claimed
WO-2018187503-A1 METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED IMPAIRMENTS USING CCR3-INHIBITORS ALKAHEST, INC. (US) 2018-10-11 WO claimed
EP-0568993-B1 Chemical amplification resist composition KYOWA HAKKO KOGYO KK (JP) 1998-08-12 EP claimed
US-5527659-A PHOTOSENSITIVITY KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-06-18 US claimed
EP-0568993-A2 Chemical amplification resist composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-11-10 EP claimed
EP-1267338-B1 Optical recording medium, optical recording method and optical recording device RICOH KK (JP) 2010-04-07 EP disclosed
EP-1449890-B1 Squarylium-metal chelate compounds and optical recording media RICOH KK (JP) 2007-09-19 EP disclosed
US-7223521-B2 Squarylium-metal chelate compounds and optical recording media RICOH COMPANY, LTD. (JP) 2007-05-29 US disclosed
US-6936323-B2 Optical recording medium, and method and device using the same RICOH COMPANY, LTD. (JP) 2005-08-30 US disclosed
US-20040265645-A1 Optical recording medium, and method and device using the same RICOH COMPANY, LTD. (JP) 2004-12-30 US disclosed
US-20040202098-A1 Squarylium-metal chelate compounds and optical recording media RICOH COMPANY, LTD. (JP) 2004-10-14 US disclosed
EP-0568993-B1 Chemical amplification resist composition KYOWA HAKKO KOGYO KK (JP) 1998-08-12 EP disclosed
US-5527659-A PHOTOSENSITIVITY KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-06-18 US disclosed
EP-0568993-A2 Chemical amplification resist composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-11-10 EP disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
EP-0452811-A2 Package of photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-10-23 EP disclosed
US-4769316-A Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 US disclosed