Sugi Predict

Sugi Predict / Compounds / Deoxyguanosine

Deoxyguanosine

Deoxyguanosine

SCHEMBL3360864

NP(O)O.Nc1nc2c(ncn2C2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.63
▸ PNP P00491 1/20 0.59
▸ LMNA P02545 1/20 0.59
▸ TP53 P04637 1/20 0.59
▸ HTT P42858 1/20 0.59
▸ PDE4D Q08499 1/20 0.59
▸ PDE3A Q14432 1/20 0.59
▸ SMN1; SMN2 Q16637 1/20 0.59
▸ RXFP1 Q9HBX9 1/20 0.59
▸ POLA1 P09884 1/20 0.58
▸ ADRB1 P08588 1/20 0.56
▸ DNMT1 P26358 1/20 0.56
▸ P2RY2 P41231 1/20 0.53
▸ P2RY4 P51582 1/20 0.53
▸ P2RY6 Q15077 1/20 0.53
▸ HIF1A Q16665 1/20 0.50
▸ ADORA3 P0DMS8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxyguanosine SCHEMBL9561816 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL14208980 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL13318963 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL22992402 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL9396414 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL23225364 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL20615 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL23892102 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL10068103 0.96 POLB (0.67) POLBPNPLMNATP53HTT
Deoxyguanosine SCHEMBL1981362 0.96 POLB (0.67) POLBPNPLMNATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12406750-B2 Encoding digital data using oligonucleotides LENOVO (SINGAPORE) PTE. LTD. (SG) 2025-09-02 — — US disclosed
US-20250078958-A1 ENCODING DIGITAL DATA USING OLIGONUCLEOTIDES LENOVO (SINGAPORE) PTE. LTD. (SG) 2025-03-06 — — US disclosed
US-20240286104-A1 POLYANILINE COATED ELECTRODES FOR POLYMER SYNTHESIS LENOVO (SINGAPORE) PTE. LTD. (SG) 2024-08-29 — — US disclosed
US-8247540-B2 Caged nucleotides and oligonucleotides and their application DEITERS ALEXANDER (US) 2012-08-21 — — US disclosed
US-20100099159-A1 CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION DEITERS ALEXANDER 2010-04-22 — — US disclosed
US-7557069-B2 Combinatorial synthesis on arrays STRATHMANN MICHAEL PAUL 2009-07-07 — — US disclosed
US-7252938-B2 Methods and devices for producing a polymer at a location of a substrate AGILENT TECHNOLOGIES, INC. (US) 2007-08-07 — — US disclosed
EP-1458907-A4 COMBINATORIAL SYNTHESIS ON ARRAYS STRATHMANN MICHAEL (US) 2007-05-09 — — EP disclosed
US-20060231412-A1 Combinatorial synthesis on arrays STRATHMANN MICHAEL P 2006-10-19 — — US disclosed
US-20060057736-A1 Methods and devices for fabricating chemical arrays AGILENT TECHNOLOGIES, INC. 2006-03-16 — — US disclosed
EP-1458907-A2 COMBINATORIAL SYNTHESIS ON ARRAYS Strathmann, Michael (US) 2004-09-22 — — EP disclosed
US-20040166496-A1 Methods and devices for producing a polymer at a location of a substrate AGILENT TECHNOLOGIES, INC. 2004-08-26 — — US disclosed
WO-2003052383-A2 COMBINATORIAL SYNTHESIS ON ARRAYS STRATHMANN MICHAEL (US) 2003-06-26 — — WO disclosed
US-20030111356-A1 Applying a barrier to a reaction on a substrate wherein the presence of the barrier is determined by an electrochemical process; polymer arrays STRATHMANN MICHAEL PAUL (US) 2003-06-19 — — US disclosed
US-20020034830-A1 Method for synthesizing a specific, surface-bound polymer uniformly over an element of a molecular array EARHART JONATHAN P (US) 2002-03-21 — — US disclosed
US-20010029296-A1 Minimization of blooming in high-density arrays by using reactive wash reagents PERBOST MICHEL G M (US) 2001-10-11 — — US disclosed
US-6300137-B1 APPLYING CAPPING AGENT TO THE SUBSTRATE TO DEACTIVATE ANY UNREACTED DEPROTECTED BOUND OLIGONUCLEOTIDE, 5'-PROTECTED NUCLEOSIDE PHOSPHORAMIDITES ARE APPLIED IN DROPLETS HAVING COVERING VOLUMES TO FULLY COVER THE FIRST DROPLET; ACCURACY AGILENT TECHNOLOGIES INC. 2001-10-09 — — US disclosed
US-6184347-B1 Minimization of blooming in high-density arrays by using reactive wash reagents AGILENT TECHNOLOGIES INC. 2001-02-06 — — US disclosed
WO-1989009778-A1 OLIGONUCLEOTIDE CONTAINING 6-THIOGUANINE AT A PREDETERMINED SITE CHEMICAL INDUSTRY INSTITUTE OF TOXICOLOGY (US) 1989-10-19 — — WO disclosed
WO-1989009780-A1 SITE-SPECIFIC TRITIUM-LABELED OLIGODEOXYNUCLEOTIDES CHEMICAL INDUSTRY INSTITUTE OF TOXICOLOGY (US) 1989-10-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099159-A1 CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION RNGTT, NT5C3B, ADAR POLB 60/4885PNP 19/4885LMNA 878/4885
US-20240286104-A1 POLYANILINE COATED ELECTRODES FOR POLYMER SYNTHESIS POLRMT, NSUN2, POLI POLB 30/4885PNP 497/4885LMNA 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.