Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362115 | 0.93 | PDE4B (0.36) | GRIK1GRIK2PDE2APDE9AKDM4E | |
| SCHEMBL3360208 | 0.91 | ICMT (0.35) | ICMTMAPK1HSD17B10TDP1CNR1 | |
| SCHEMBL3361360 | 0.90 | MEN1 (0.33) | ICMTPDE2APDE9ATDP1CNR2 | |
| SCHEMBL3469903 | 0.86 | PDE4B (0.39) | GRIK1GRIK2KDM4EALDH1A1HPGD | |
| SCHEMBL3360263 | 0.84 | PDE4B (0.35) | POLBICMTPDE2APDE9AKDM4E | |
| SCHEMBL3359268 | 0.83 | CRHR1 (0.34) | KDM4EHSD17B10PDE4BPDE4DTDP1 | |
| SCHEMBL3468899 | 0.83 | CRHR1 (0.34) | KDM4EHSD17B10PDE4BPDE4DTLR8 | |
| SCHEMBL3363585 | 0.82 | CA12 (0.34) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3474171 | 0.82 | PDE4B (0.34) | KDM4EHSD17B10PDE4BPDE4DTDP1 | |
| SCHEMBL3364964 | 0.82 | ICMT (0.33) | ICMTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210887-A1 | Bis resorcinyl triazine derivatives as protecting agents against UV radiation | ISDIN, S.A. (ES) | 2010-07-28 | — | — | EP | disclosed |
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |