SCHEMBL3362115

SCHEMBL3362115

CCCCC(CC)Cn1cc(-c2nc(-c3ccc(O)c(C)c3O)nc(-c3ccc(O)c(C)c3O)n2)c2cc(OC)ccc21

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 3/20 0.36
PDE4D Q08499 3/20 0.36
ABCC2 Q92887 1/20 0.34
TLR8 Q9NR97 1/20 0.33
CRHR1 P34998 4/20 0.33
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 2/20 0.33
NPC1 O15118 2/20 0.32
CNR2 P34972 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
PDE2A O00408 1/20 0.32
PDE9A O76083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360889 0.93 MGLL (0.33) PDE4BPDE4DTLR8KDM4EHSD17B10
SCHEMBL3469903 0.93 PDE4B (0.39) PDE4BPDE4DCRHR1KDM4EHSD17B10
SCHEMBL3359268 0.89 CRHR1 (0.34) PDE4BPDE4DABCC2TLR8CRHR1
SCHEMBL3468899 0.89 CRHR1 (0.34) PDE4BPDE4DABCC2TLR8CRHR1
SCHEMBL3474171 0.88 PDE4B (0.34) PDE4BPDE4DABCC2TLR8CRHR1
SCHEMBL3468874 0.88 CRHR1 (0.33) PDE4BPDE4DABCC2TLR8CRHR1
SCHEMBL3469068 0.88 CRHR1 (0.34) PDE4BPDE4DABCC2TLR8CRHR1
SCHEMBL3469137 0.86 ABCC2 (0.45) PDE4BPDE4DABCC2TLR8KDM4E
SCHEMBL3363585 0.85 CA12 (0.34) KDM4EHSD17B10CNR2ALDH1A1HPGD
SCHEMBL3360208 0.85 ICMT (0.35) HSD17B10CNR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed