Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174867 | 0.84 | ALDH1A1 (0.55) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL13537217 | 0.81 | KDM4E (0.41) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL1431441 | 0.79 | ALDH1A1 (0.48) | KDM4EKMT2AMAPTTDP1MEN1 | |
| SCHEMBL21277619 | 0.78 | KDM4E (0.63) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL27793256 | 0.77 | ALDH1A1 (0.46) | KDM4EKMT2AMAPTTDP1MEN1 | |
| SCHEMBL28640055 | 0.77 | MAPT (0.54) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL107833 | 0.77 | KMT2A (0.95) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL352643 | 0.77 | KMT2A (1.00) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL29498389 | 0.77 | KMT2A (1.00) | KDM4EKMT2AGFERRXFP1MAPT | |
| SCHEMBL1954450 | 0.77 | KMT2A (1.00) | KDM4EKMT2AGFERRXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111195241-A | Folic acid modified starch microcapsule with reduction responsiveness and preparation method thereof | 黄冈华阳药业有限公司 | 2020-05-26 | — | — | CN | claimed |
| CN-105326810-A | Folic acid modified chitosan micro-capsule with reducing responsiveness and preparation method thereof | UNIV JILIN | 2016-02-17 | — | — | CN | claimed |
| CN-105310998-A | Microcapsule containing functionalized graphene in capsule wall and preparation method of microcapsule | UNIV JILIN | 2016-02-10 | — | — | CN | claimed |
| CN-103739533-A | Method for preparing 2-amido-5-thiobenzoic acid | UNIV TAIYUAN TECHNOLOGY | 2014-04-23 | — | — | CN | claimed |
| EP-0170838-B1 | REACTIVE DYES OF THE DIOXAZINE-TYPE, THEIR PREPARATION AND USE | BAYER AG (DE) | 1989-07-12 | — | — | EP | claimed |
| US-20220380339-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2022-12-01 | — | — | US | disclosed |
| US-20210188808-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2021-06-24 | — | — | US | disclosed |
| US-10968202-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | XW LABORATORIES INC. (KY) | 2021-04-06 | — | — | US | disclosed |
| US-20200369645-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2020-11-26 | — | — | US | disclosed |
| US-10730853-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | XW LABORATORIES INC. (KY) | 2020-08-04 | — | — | US | disclosed |
| US-20200181112-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | XWPharma Ltd. (KY) | 2020-06-11 | — | — | US | disclosed |
| CN-111195241-A | Folic acid modified starch microcapsule with reduction responsiveness and preparation method thereof | 黄冈华阳药业有限公司 | 2020-05-26 | — | — | CN | disclosed |
| WO-2005064008-A9 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES INC (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | GILEAD SCIENCES. INC. | 2005-10-27 | — | — | US | disclosed |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. | 2005-09-22 | — | — | US | disclosed |
| WO-2005064008-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| EP-1509537-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-5409916-A | Brilliant violet shades; free of heavy metals | HOECHST CELANESE CORPORATION (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1994029283-A1 | FIBER REACTIVE ANTHRAQUINONE DYES | HOECHST CELANESE CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380339-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | HRH3, HRH4, HRH2 | KDM4E 2022/4885KMT2A 691/4885GFER 627/4885 |
| US-20200181112-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | HRH3, HRH4, HRH2 | KDM4E 2153/4885KMT2A 621/4885GFER 988/4885 |
| US-10968202-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | HRH3, HRH4, HRH2 | KDM4E 2153/4885KMT2A 621/4885GFER 988/4885 |
| US-20200369645-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | HRH3, HRH4, HRH2 | KDM4E 2153/4885KMT2A 621/4885GFER 988/4885 |
| US-20210188808-A1 | COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF | HRH3, HRH4, HRH2 | KDM4E 2153/4885KMT2A 621/4885GFER 988/4885 |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | PPA1, PPME1, PNP | KDM4E 3407/4885KMT2A 3702/4885GFER 3568/4885 |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | CES1, PNP, PGLS | KDM4E 1006/4885KMT2A 4457/4885GFER 1235/4885 |
| US-10730853-B2 | Compounds as neuronal histamine receptor-3 antagonists and uses thereof | HRH3, HRH4, HRH2 | KDM4E 2153/4885KMT2A 621/4885GFER 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.