Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 16/20 | 0.61 |
| ▸ | DDO | Q99489 | 8/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360159 | 0.88 | DAO (0.58) | DAODDOIDO1TDO2ERCC1 | |
| SCHEMBL3424908 | 0.88 | DAO (0.53) | DAODDO | |
| SCHEMBL3360150 | 0.85 | DAO (0.59) | DAODDOERCC1ERCC4 | |
| SCHEMBL3421760 | 0.85 | DAO (0.55) | DAODDOPGR | |
| SCHEMBL3419432 | 0.83 | DAO (0.51) | DAODDOPGR | |
| SCHEMBL9388997 | 0.80 | DAO (0.66) | DAODDO | |
| SCHEMBL9388973 | 0.79 | DAO (0.56) | DAODDOERCC1ERCC4 | |
| SCHEMBL9389846 | 0.77 | DAO (0.49) | DAODDO | |
| SCHEMBL3359992 | 0.76 | GRIN2D (0.48) | DAODDO | |
| SCHEMBL3362300 | 0.76 | DAO (1.00) | DAODDOHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |