Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 15/20 | 0.67 |
| ▸ | DDO | Q99489 | 9/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361024 | 0.83 | DAO (0.71) | DAODDO | |
| SCHEMBL16767851 | 0.80 | DAO (1.00) | DAODDO | |
| SCHEMBL3418547 | 0.80 | DAO (0.61) | DAODDOTSHRHSD17B10MAPT | |
| SCHEMBL3363456 | 0.76 | DAO (1.00) | DAODDOHRH4MAPT | |
| SCHEMBL1406090 | 0.74 | KEAP1 (0.50) | HRH4TSHRHSD17B10MAPTHTT | |
| SCHEMBL3433397 | 0.73 | DAO (0.67) | DAODDO | |
| SCHEMBL3100612 | 0.73 | HRH4 (0.60) | DAOHRH4TSHRHSD17B10 | |
| SCHEMBL3424908 | 0.73 | DAO (0.53) | DAODDOHSD17B10 | |
| SCHEMBL3395093 | 0.73 | DAO (0.67) | DAODDOHRH4 | |
| SCHEMBL3363037 | 0.73 | DAO (0.61) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |