Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.67 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3364779 | 0.99 | DPP4 (0.68) | DPP4PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL3362414 | 0.86 | DPP4 (0.61) | DPP4PDE10AALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL3361903 | 0.85 | DPP4 (0.62) | DPP4PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL3365216 | 0.84 | DPP4 (0.58) | DPP4PDE10AALDH1A1RAB9APOLB | |
| SCHEMBL3365143 | 0.84 | PDE10A (0.51) | DPP4PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL7716787 | 0.81 | DPP4 (1.00) | DPP4PDE10AALDH1A1HPGDPOLB | |
| SCHEMBL3360594 | 0.76 | DPP4 (0.71) | DPP4 | |
| SCHEMBL3365202 | 0.74 | DPP4 (0.44) | DPP4PDE10AALDH1A1HPGDKDM4E | |
| SCHEMBL17581348 | 0.73 | HPGD (0.53) | ALDH1A1HPGDKDM4EPKMKLKB1 | |
| SCHEMBL3361845 | 0.72 | DPP4 (1.00) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | claimed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |