SCHEMBL317622

SCHEMBL317622

O=c1cc(Cl)[nH]c(=O)[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11678739 0.74
SCHEMBL17347251 0.72
SCHEMBL1316501 0.69
SCHEMBL317706 0.67 GPR84 (0.50)
SCHEMBL8974784 0.67 GPR84 (0.50)
SCHEMBL18836780 0.67 GPR84 (0.52)
SCHEMBL9242561 0.67 GPR84 (0.52)
SCHEMBL4561073 0.67 GPR84 (0.50)
SCHEMBL11726927 0.67 CA1 (0.44)
SCHEMBL6999959 0.67 KDM4C (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
CN-119019364-A Uracil derivative and preparation method and application thereof 石河子大学 2024-11-26 CN claimed
CN-115785080-B Uracil parent nucleus compound and preparation method and application thereof 陕西盘龙药业集团股份有限公司 2024-10-11 CN claimed
CN-118440053-A QC and DPP-4 dual-targeting inhibitor and preparation method and application thereof 深圳大学 2024-08-06 CN claimed
CN-116626190-A Method for detecting halogenated base in drinking water by solid phase extraction-liquid chromatography tandem mass spectrometry 浙江大学 2023-08-22 CN claimed
US-20230133044-A1 THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS BROWN DENNIS M (US) 2023-05-04 US claimed
CN-115785080-A Uracil parent nucleus compound and preparation method and application thereof 陕西盘龙药业集团股份有限公司 2023-03-14 CN claimed
CN-115448887-A Trelagliptin succinate intermediate impurity and preparation method and application thereof 河北国龙制药有限公司 2022-12-09 CN claimed
WO-2014168986-A1 THERAPEUTIC BENEFIT OF SUBOPTIMALLY ADMINISTERED CHEMICAL COMPOUNDS BROWN DENNIS M (US) 2014-10-16 WO claimed
CN-103804694-A Polymer gene transfection vector based on nucleic acid base derivative and preparation method and application thereof UNIV EAST CHINA NORMAL 2014-05-21 CN claimed
CN-103193762-A Preparation method of alogliptin benzoate SHANDONG LUOXIN PHARMACY STOCK 2013-07-10 CN claimed
US-20100284954-A1 PROCESS FOR RELAXING KERATIN FIBRES L'OREAL (FR) 2010-11-11 US claimed
US-7795428-B2 Dipeptidyl peptidase inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-09-14 US claimed
EP-1586571-B1 Dipeptidyl peptidase inhibitors TAKEDA PHARMACEUTICAL (JP) 2008-07-16 EP claimed
US-20080003283-A1 DIPEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY, INC. (JP) 2008-01-03 US claimed
US-20060127337-A1 Process for relaxing keratin fibres L'OREAL (FR) 2006-06-15 US claimed
EP-1586571-A1 Dipeptidyl peptidase inhibitors Takeda San Diego, Inc. (US) 2005-10-19 EP claimed
WO-2005095381-A1 DIPEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-10-13 WO claimed