Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.69 |
| ▸ | DRD2 | P14416 | 4/20 | 0.69 |
| ▸ | DRD3 | P35462 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.69 |
| ▸ | HTR3A | P46098 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clebopride SCHEMBL25259199 | 0.82 | DRD4 (1.00) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| Clebopride SCHEMBL25710 | 0.82 | DRD4 (1.00) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| Clebopride SCHEMBL9867307 | 0.81 | DRD4 (0.98) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| SCHEMBL15650737 | 0.80 | HTR4 (0.83) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| SCHEMBL11472928 | 0.78 | DRD4 (1.00) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| Clebopride SCHEMBL2323732 | 0.78 | CYP3A4 (1.00) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| Clebopride SCHEMBL4537448 | 0.78 | CYP3A4 (1.00) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| Clebopride SCHEMBL2323725 | 0.78 | CYP3A4 (1.00) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| SCHEMBL11533888 | 0.78 | DRD4 (0.92) | DRD4DRD2DRD3CYP3A4CYP1A2 | |
| SCHEMBL7345151 | 0.77 | DRD4 (0.72) | DRD4DRD2DRD3CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | DRD4 82/4885DRD2 59/4885DRD3 80/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | DRD4 2928/4885DRD2 3870/4885DRD3 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.