Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578644 | 0.85 | ESR1 (0.42) | ESR1ESR2KDM4ECNR1CNR2 | |
| SCHEMBL2581042 | 0.84 | ESR1 (0.37) | ESR1ESR2KDM4ETP53CYP3A4 | |
| SCHEMBL7910678 | 0.83 | RAB9A (0.40) | ESR1ESR2CNR1CNR2RAB9A | |
| SCHEMBL2464168 | 0.83 | ESR1 (0.35) | ESR1ESR2KDM4ETP53CYP3A4 | |
| SCHEMBL2464167 | 0.83 | ESR1 (0.34) | ESR1ESR2KDM4ETERTMTNR1A | |
| SCHEMBL2586745 | 0.83 | ESR1 (0.36) | ESR1ESR2CNR1CNR2RAB9A | |
| SCHEMBL2586818 | 0.81 | ESR1 (0.34) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL2464402 | 0.79 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL7909989 | 0.79 | ESR1 (0.39) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2578962 | 0.78 | ESR1 (0.38) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |