Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 3/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362491 | 0.83 | ESR1 (0.38) | ESR1ESR2CNR1CNR2MTNR1A | |
| SCHEMBL2461978 | 0.76 | CHRM1 (0.40) | CNR1CNR2MTNR1AMTNR1BKDM4E | |
| SCHEMBL2578644 | 0.69 | ESR1 (0.42) | ESR1ESR2CNR1CNR2KDM4E | |
| SCHEMBL2464167 | 0.68 | ESR1 (0.34) | ESR1ESR2MTNR1AMTNR1BKDM4E | |
| SCHEMBL2581042 | 0.68 | ESR1 (0.37) | ESR1ESR2CNR1CNR2KDM4E | |
| SCHEMBL7910678 | 0.68 | RAB9A (0.40) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL2460915 | 0.67 | MGAM (0.34) | KDM4E | |
| SCHEMBL2586745 | 0.67 | ESR1 (0.36) | ESR1ESR2CNR1CNR2 | |
| SCHEMBL12160478 | 0.66 | ESR1 (0.38) | ESR1ESR2CNR1CNR2EDNRA | |
| SCHEMBL2586818 | 0.65 | ESR1 (0.34) | ESR1ESR2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |