Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 4/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424196 | 0.84 | KMO (0.35) | PSMB8PSMB9PSMB5L3MBTL1KMO | |
| SCHEMBL3363702 | 0.82 | ABL1 (0.34) | PSMB8PSMB9PSMB5L3MBTL1KMO | |
| SCHEMBL3422558 | 0.80 | ABL1 (0.37) | L3MBTL1KMORORCHPGDABL1 | |
| SCHEMBL3396241 | 0.80 | CTSK (0.34) | PSMB8PSMB9PSMB5L3MBTL1KMO | |
| SCHEMBL3362566 | 0.80 | PSMB8 (0.34) | PSMB8PSMB9PSMB5PTGESKMO | |
| SCHEMBL3363705 | 0.76 | L3MBTL1 (0.34) | PSMB8PSMB9PSMB5L3MBTL1KMO | |
| SCHEMBL10203078 | 0.69 | SCN5A (0.34) | — | |
| SCHEMBL11529071 | 0.68 | MLYCD (0.37) | PSMB8PSMB9PSMB5 | |
| SCHEMBL27283627 | 0.68 | PSMB8 (0.34) | PSMB8PSMB9PSMB5PTGESLMNA | |
| SCHEMBL2262247 | 0.67 | L3MBTL1 (0.38) | PSMB5L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |